2. Who is Who?
  3. Champagne Viticulture
  4. JEANDET Philippe

JEANDET Philippe

Contact details

Professor of University (Biochemistry and Molecular Biology, 64th section of the National Council of the Universities)

Research Unit “Induced Resistance and Plant Bioprotection”, RIBP-USC INRAe 1488

Faculty of Sciences, University of Reims Champagne-Ardenne

51100 Reims, France

Mail: philippe.jeandet@univ-reims.fr

Phone number: + 333 26 91 33 41

Research activities

Currently working on resveratrol, stilbene compounds and more generally on natural product chemistry and bioactivity

Research key words

Stilbenes; resveratrol; phytoalexins; plant-pathogens interactions; secondary metabolites; natural compounds; chemistry; bioactivity

Technical skills

Gas chromatography and ultra-high-performance liquid chromatography, chemical extraction of natural productss

Teaching activities

My teaching activities (circa 235 h per year) are carried out, respectively, at the Bachelor of Science level, the National Diploma of Oenology, the Master of Grapevine and Wine Science and the Master degree in Wine and Spirits Law. My teaching skills are the following:

  • Anatomy and chemical composition of grapes
  • Biochemistry of the maturation process of grape berries (biosynthesis and metabolism of sugars, organic acids, nitrogen compounds and polyphenolics)
  • Enzymatic activities of the grape berry (pectinases, oxidoreductases)
  • Wine chemistry
  • Tartaric acid salts stabilization process
  • Principles of winemaking

I am currently head of the Master of Grapevine and Wine Science, the Wine and Champagne Master degree as well as the head of the oenology program in the Bachelor of Science degree

Teaching key words

Biochemistry of the grape berry, anatomy, enzymatic activities of the grape berry, wine chemistry, chemical composition of wine, stabilization, winemaking, wine, champagne

Coordination of national and international projects in relation to vine and wine

2007-2014

Coordinator of the VINEAL 2 Program (French government/ Champagne-Ardenne regional council project, CPER 2007-2013) entitled « Grapevine diseases: Alternative strategies to the use of pesticides. Grape and wine proteome and physico-chemical study of the effervescence and the foaming properties of champagne wines». 20 different academic institutions (French and foreign universities, CNRS, INRA) and six companies, representing at least 100 scientists, were allocated to this federative project. Its total budget was 15 117 340 €. A financial support of 2 618 340 € was allocated to this research program (6 PhD and 6 post-docs.)

2007-2014

Head of theme 2 of the VINEAL 2 Program (French government/Champagne-Ardenne regional council project, CPER 2007-2013) entitled «Grape and wine proteome and physico-chemical study of the effervescence and the foaming properties of champagne wines» (2 PhD and 2 post-docs).

2013-2018

Co-Leader of a research group on grapevine phytoalexins (Unit RIBP)

2021-2023

Adjunct Coordinator for the University of Reims of the research program entitled «ResEx-Extreme Resolution Mass Spectrometry» - FEDER-FSE Lorraine et Massif des Vosges 2014-2020 dedicated to Mass Spectrometry Imaging of complex phytoalexins in stressed grapevine

Main recent articles

- Jeandet P., Heinzmann S., Roullier Gall C., Cilindre C., Aron A., Deville M.A., Moritz F., Karbowiak T., Demarville D., Brun C., Moreau F., Michalke B., Liger-Belair G., Witting M., Lucio M., Steyer D., Gougeon R.D. and Schmitt-Kopplin P. Chemical messages in 170-year-old champagne bottles from the Baltic Sea: Revealing tastes from the past. Proceedings of the National Academy of Sciences USA, 2015, 112, 5893-5898.

- Jeandet P., Sobarzo-Sánchez E., Clément C., Nabavi S.F., Habtemariam S., Nabavi S.M. and Cordelier S. Engineering stilbene metabolic pathways in microbial cells. Biotechnology Advances, 2018, 36, 2264-2283.

- Jeandet P., Clément C. and Cordelier S. Regulation of resveratrol biosynthesis in grapevine: new approaches for disease resistance? Journal of Experimental Botany, 2019, 70, 375-378.

- Jeandet P., Sobarzo-Sánchez E., Sanches Silva A., Clément C., Nabavi S.F., Battino M., Rasekhian M., Belwal T., Habtemariam S., Koffas M. and Nabavi S.M. Whole-cell biocatalytic, enzymatic and green chemistry methods for the production of resveratrol and its derivatives. Biotechnology Advances, 2020, 38, 107461.

- Jeandet P., Vannozzi A., Sobarzo-Sanchez E., Uddin M.S., Bru R., Martinez-Marquez A., Clément C., Cordelier S., Manayi A., Nabavi S.F., Rasekhian M., Batiha G.E.S., Khan H., Morkunas I., Belwal T., Jiang J., Koffas M. and Nabavi S.M. Phytostilbenes as agrochemicals: biosynthesis, bioactivity, metabolic engineering and biotechnology. Natural Product Reports, 2021, 28, 1282-1329.

- Jeandet P., Sobarzo-Sanchez E., Uddin M.S., Bru R., Clément C., Jacquard C., Nabavi S.F., Khayatkashani M., Batiha G.E.S., Khan H., Morkunas I., Trotta F., Matencio A. and Nabavi S.M. Resveratrol and cyclodextrins, an easy alliance: Applications in nanomedicine, green chemistry and biotechnology. Biotechnology Advances, 2021, 53, 107844.

- Jeandet P., Formela-Luboińska M., Labudda M. and Morkunas M. The role of sugars in plant responses to stress and their regulatory function during development. International Journal of Molecular Sciences, 2022, 23, 5161.

- Jeandet P., Kumar, V. and Tewari D. Opportunities and challenges for drug discovery from natural products in pharmacotherapy of neurological disorders. Frontiers in Neuroscience, 2022, 16, 936981.

- Jeandet P., Uddin M.S., Clément C., Aziz A., Jacquard C., Khan H., Shah M.A., Ait-Barka E., Koffas M., Nabavi S.M., Sobarzo-Sanchez E. and Renault J.H. Production of high molecular-ordered stilbene oligomers: Total synthesis, bio-catalyzed synthesis and production by plant systems. Natural Product Reports, 2023, 40, 1045-1057.

Recent international conferences

Jeandet P., Heinzmann S., Roullier Gall C., Cilindre C., Aron A., Deville M.A., Moritz F., Karbowiak T., Demarville D., Brun C., Moreau F., Michalke B., Liger-Belair G., Witting M., Lucio M., Steyer D., Gougeon R.D. and Schmitt-Kopplin P. Metabolomics, metallomics and sensorial analysis reveal the composition of 170-year-old champagne bottles from the Baltic sea. IXth In Vino Analytica Scientia Symposium, Trento, Italy, 2015.

Roullier-Gall C., Hemmler D., Witting M., Moritz F., Heinzmann S., Jeandet P., Gonsior M., Gougeon R. and Schmitt-Kopplin P. Metabolomic characterization of bottled wines: Impact of environmental parameters. Congress of the American Chemical Society, Philadelphia, USA, 2016.

Jeandet P., Nivelle L., Tisserant L.P., Hubert J., Clément C., Boitel M., Delmas D., Tarpin M. and Courot E. Anticancer activity of resveratrol and related hydroxystilbenes bioproduced by grapevine cell systems. Third International Symposium Wine and Health (III Symposio Internacional Vinho E Saude), Bento Gonçalvez, Brazil, 2017.

Jeandet P., Hubert J., Nivelle L., Renault J.H., Nuzillard J.M., Tarpin M., Martiny L., Clément C. and Courot E. Developing biotechnological approaches for the production and the characterization of oligomeric stilbenes allowing evaluation of their biological activity. Possible applications to cosmetology, Cosm’ing, Cosmetic and Biotechnology 2018 Congress, Saint-Malo, France, 2018.

Maia M., Aziz A., Jeandet P. and Carré V. Metabolic snapshot of grapevine-pathogen interactions through mass spectrometry imaging. XIII International Symposium on Grapevine Breeding and Genetics, Landau, Germany, 2022.

Maia M., Aziz A., Jeandet P. and Carré V. The quest for phytoalexin response and location by MALDI-MSI during grapevine-pathogen interactions. Analytics, Nantes, France, 2022.

My research activities have led to 300 articles with around 200 published in journals indexed in the Journal Citation Reports, of which 75 have been published since 2015, one international patent, 270 communications to numerous Symposia or Congresses, the organization of three international symposia and the creation of a series of Symposia entitled Macromolecules and Secondary Metabolites of Grapevine and Wine. I have edited three books and 15 special issues. I am (or have been) member of the editorial committees of 15 different academic journals and occasional referee for 75 different scientific journals. I am ranked in the Top 1% of the most influential researchers in the world (world's list of the most influential researchers for the years 2021 and 2022 published by Stanford University, using Scival (Elsevier) platform data).

https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/4?fbclid=IwAR3QePqXxp_atsW05kUvP2SPlRIC_MZTZXeeUJJQHtHM6jFMef_XjRbcFxE
I am also ranked #398 in France (Best Biology and Biochemistry Scientists in France) and #11057 in the world (world ranking in the field of Biology and Biochemistry (Research.com)) https://research.com/scientists-rankings/biology-and-biochemistry/fr

https://research.com/scientists-rankings/biology-and-biochemistry

My bibliographical data are available on the two following sites:
https://scholar.google.com/citations?hl=fr&user=d_m3kL0AAAAJ&view_op=list_works
http://www.researchgate.net/profile/Philippe_Jeandet