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Interactions Cells-Parasites: Biodiversity, Pathogenesis, Resistance (ICP)

Contact details

Interactions Cellules-Parasites : Biodiversité, Pathogénie, Résistance (ICP)
UFR Médecine
51, rue Cognacq Jay
51090 REIMS cedex
FRANCE

 


Presentation


Personnel : 10 persons including 6 with post-doctorate

Key Words
Parasite - pathogeny - resistance to medication - virulence-proteases – therapeutic targets

Know-How

  • Cellular culture
  • Antigen/antibodies detection
  • Molecular biology (conventional and real time)
  • Large-volume water filtration for immunomagnetic parasite separation
  • Protein purification
  • Flow cytometry
  • Bidimensional electrophoresis


Research subjects

  • Antiparasite resistance mechanisms
  • Membrane transport
  • Virulence factor (metallo-proteinases)
  • Extra cellular membrane transfer
  • Pathogens
  • Parasites in the environment.


Equipment

  • Molecular biology
  • Cellular culture
  • Conventional and transgenic small animals
  • Specific equipment for antigen-antibodies analysis


Patents

  • In progress
    • T.gondii parasite ABC-carrier-type protein (efflux, resistance …)


Partnerships

  • INDUSTRIAL
    • PALL LIFE Sciences
    • ARGENE BIOSOFT
    • ABBOTT Diagnostics…
  • ACADEMIC
  • 33 CHUs within Toxoplasmose CNR & Toxoplasma CRB projects
  • Special partnerships: Limoges, Grenoble, Paris VI
  • OTHERS
    • Institut de Veille Sanitaire


Specificities

  • Toxoplasma Biological Resource Centre (supported by Research Ministry and Inserm)
  • Toxoplasmose National Reference Centre (national coordinator: I. Villena)
  • Toxoplasme Biological Resource Centre, unique in France
ISABELLE VILLENA
Directrice
Phone 03.26.91.80.86