Keywords: Biobank, Collection, Conservation, CRB, Samples, Sampling, Research, Biological resources, Human health, Biological sciences, Strains, Tumors, Paraffin blocks, Tissues, Cells, Cancer, Agronomy.
PRESENTATION
What is a BRC or a Biobank?
A BRC (Biological Resource Center), also called Biobank, referred to structured collections of biological samples and associated data, stored for the purposes of present and future research.
A BRC manages the preparation, conservation and provision of Biological Resources (samples and associated data) for scientific purposes.
It can also build collections and make them available to researchers within the framework of clinical or fundamental research projects
The PF CRBs of Reims (Platform of Biological Resource Centers of Reims)
The PF CRBs Reims created in 2020 is a multithematic biobank by the administrative union of the three main Biobanks of Champagne Ardenne Area, the CRB CHAR, the CRB-TCA (certified since February 2016) and the CRB Toxoplama (certified since January 2010). The PF CRBs Reims collections are distinguished by 3 main themes:
- The human theme
- The plant theme
- The microbial theme
The PF CRBs Reims is under the joint management of the Reims University Hospital and the University of Reims Champagne-Ardenne (URCA). The scientific directors of the PF CRBs Reims are Prof. Isabelle VILLENA and Prof. Aude MARCHAL (Dr Anne DURLACH by delegation).
THE PF CRBs REIMS TEAM
Pr Isabelle Villena - Scientific co-manager of PF CRBs Reims
Pr Aude MARCHAL (Dr Anne DULRACH by delegation) - Scientific co-manager of PF CRBs Reims
Isabelle Rapacz - Executive of the PF CRBs Reims
Saviz Nasri - Coordinating engineer of the PF CRBs Reims
Camila Rocaboy - Quality engineer of PF CRBs Reims
Christelle Coquelet - PF CRBs Reims technician
QUALITY COMMITMENT
The PF CRBs Reims, mindful of the needs and expectations of its stakeholders (patients, users and investigators), is committed to a process of structuring and continuous quality improvement according to the requirements of ISO 20 387 and ISO 9001 standards.
The organization of the PF CRBs Reims is governed by a charter to which any person wishing to set up a collection or access biological resources adheres.
This charter defines the commitments and obligations of the initiator of the collection, the user of the resources and the PF CRBs Reims. Impartiality and integrity are an integral part of the quality management system of PF CRBs Reims.
MISSIONS OF THE PF CRBs REIMS
- Reception, preparation and safe storage of samples under quality assurance.
- Samples are processed in accordance with the technical protocols defined in advance for the recovery of different types of samples. The samples are kept within the two constituent sites of the PF CRBs (CHU and URCA) depending on the nature of the collections.
- Recording of the data associated with the samples stored in the TumoroteK® software (particularly the location of the samples in the storage enclosures).
- Provision, free of charge or fee based, of biological resources to the scientific community, to industries in the field of health, agronomy or biotechnology.
- After examination of the request, an estimate and a supply contract are proposed. Upon signature of the documents, the samples accompanied by their data are sent.
- Promotion of Biological Resources in publications, scientific communications and participation in national and international networks.
PF CRBs Reims can also provide services for other teams and other organizations.
The missions of the PF CRBs Reims are carried out in compliance with regulations (ISO 20 387 and ISO 9001) and the protection of individuals (patient consent and anonymization of samples).
PF CRBs Reims is free from any commercial, financial and scientific influence.
Acceptance criteria for a collection
Compliance with regulations
Definition of the applicant's need
Definition of minimum sample data set
Good quality condition of the samples
Definition of sample preparation conditions
Negotiation of collection management
Signature of a contract
Criteria for access to samples
Compliance with regulations
Definition of the researcher's need
Acceptance of the request by the depositor of the collection and by the Scientific Council
Presentation of a quote
Signature of a contract
Transfer of samples and associated data
Monitoring of the use of samples and data
CATALOG OF SERVICES
PF CRBs Reims provides the following services:
- Centrifugation
- Aliquoting
- PBMCs isolation
- Preservation of whole blood, plasma, serum, LBA, urine, cells, nucleic acids, tissues, microbial strains, plant seeds etc.
CATALOG OF COLLECTIONS
To consult the PF CRBs Reims catalog
PREMISES AND EQUIPMENT
The PF CRBs Reims is located at the Pole of Medical Biology and Pathology of the Reims University Hospital.
To preserve samples, the PF CRBs Reims is equipped:
- Nitrogen tanks including 2 “Voyageurs+” (mobile tanks for transporting samples)
- Thermostatically controlled chambers at -80 ° C (+/- 10 ° C)
- Thermostatically controlled chambers at -20 ° C (+/- 5 ° C)
- Thermostatically controlled chambers at + 4 ° C (+/- 3 ° C)
- Secure storage spaces at room temperature (18-25 ° C)
The temperature of all the PF CRBs Reims’s storage chambers is controlled by using probes allowing their metrological monitoring and guaranteeing the quality of the samples stored.
MANAGEMENT OF REQUESTS FOR BIOLOGICAL RESOURCES
For all requests for biological resources, please complete the request form for biological resources, then send it to the address: pfcrbs@chu-reims.fr
All requests are evaluated and a feasibility study is carried out.
If the request is admissible by the PF CRBs Reims, it will be submitted to the Scientific Council which will act on the provision. For each request, a contract is established between the user and PF CRBs Reims.
MANAGEMENT OF REQUESTS FOR A NEW COLLECTION
For all requests for a new collection, please complete the request form, then send it to the address: pfcrbs@chu-reims.fr
All requests are evaluated and a feasibility study is carried out.
If the request is admissible by the PF CRBs Reims, it will be submitted to the Scientific Council which will act on the provision. For each request, a contract is established between the user and PF CRBs Reims.
PRICE LIST
- For a request to set up a collection, the PF CRBs Reims is based on the price list of hospital biobanks
- For any request for the provision of a sample, the price list is as follows
CONTACT
For any further information, you can reach PF CRBs Reims
by email at the following address: pfcrbs@chu-reims.fr
by mail to the following postal address:
Plateforme des Centres de Ressources Biologiques de Reims
Pôle de Biologie Territoriale du CHU de Reims – Niveau 2
Avenue du Général Koenig
51092 REIMS CEDEX